When Fertility Tests Are Normal, But Pregnancy Isn’t Happening

One of the most common stories I hear in clinic goes something like this:

“My tests are normal. My partner’s tests are normal. We’ve been told everything looks fine…”

Yet month after month, pregnancy still isn’t happening.

Now don’t get me wrong. Sometimes investigations genuinely don’t reveal an obvious cause. Fertility is complex and there are no guarantees.

But I often find myself wondering whether we’ve asked enough questions.

Because when I sit down with someone and take a detailed history, I rarely hear a story that sounds completely straightforward.

Perhaps they’ve struggled with energy for years.

Perhaps they experience strong sugar cravings, energy crashes, or find themselves relying on caffeine to get through the day.

Perhaps their periods are painful, heavy or contain clots.

Perhaps they’ve had recurrent thrush, BV or urinary tract infections.

Perhaps they’ve gained weight despite eating well and exercising regularly.

Perhaps they’ve been told their thyroid is “normal”, yet still have symptoms that leave them feeling anything but normal.

None of these things automatically explains fertility difficulties.

But they do make me curious.

Because our bodies don’t tend to develop symptoms for no reason.

What if these symptoms aren’t separate problems?

What if they’re clues?

The more I learn, the more interested I become in the connections between fertility and the rest of the body.

Blood sugar regulation.

Hormone balance.

Inflammation.

Nutrient status.

Gut health.

The vaginal and urinary microbiome.

Sleep.

Stress.

These systems don’t exist in isolation, and neither does fertility.

This is why I believe it’s important to look at the whole picture rather than focusing solely on whether a result falls within a reference range.

“Normal” is an important starting point. It’s not always the end of the conversation.

Need support?

If you’re trying to conceive, preparing for IVF, or simply feel there may be pieces of your fertility story that haven’t yet been explored, I’d love to help.

Together we can review your symptoms, health history, lifestyle factors and existing test results to identify areas that may benefit from further investigation and optimisation before taking the next step on your fertility journey. Book in today or contact me for a free discovery call.

Feel at the endo’ your rope with Endometriosis?

Woman experiencing menstrual cramping and heavy bleeding due to endometriosis.

Endometriosis is a condition where the cells of the endometrium (the uterine lining) are laid down outside of the uterus, usually within the pelvic cavity but sometimes also further afield, like in the nostril for example.

Often endometriosis is found on the ovaries, fallopian tubes, or even the bladder and bowel.

When menses occurs, the endometriosis tissue bleeds too. This means that menstrual blood is flowing into areas where it shouldn’t. The body’s immune system will kick in, and attack the endometriosis tissue, creating high levels of inflammation and pain.

Other symptoms might include pain while emptying bladder, during bowel movements, and during or after intimacy. IBS symptoms may also be present; diarrhoea or constipation.

Often endometriosis takes a long time to diagnose, because it really can only be seen via laparoscopy or MRI, although sometimes it can be detected via ultrasound. Initially pain and IBS symptoms will be dealt with via pain killers, and heavy periods are often managed via the oral contraceptive pill. Although these firefighting methods might help, they don’t get to the root of the issue.

High levels of inflammation can cause all sorts of havoc within the body. A disordered immune system will have an impact on thyroid, joints, musculo-skeletal health, intestinal and bowel health, sexual health and mental wellbeing. Higher levels of the wrong type of bacteria can be prolific within the microbiome. Oestrogen dominance can also prevail.

What are the answers?

If you suspect you have endometriosis its imperative that your symptoms are investigated further.

Anything you can do to modulate your immune system will help. Eating an anti-inflammatory diet and removing known stimulants and food triggers is important. Seek help from an Acupuncturist specialising in fertility or women’s health, or a reflexologist specialising in Reflexology Lymph Drainage.

If you are experiencing problems and would like to book in with me please get in touch.

Understanding AMH

AMH blood test.

If you are trying to conceive and gone down the “infertility road” a little way, then you may well have had your AMH levels checked. Many will call this your “ovarian reserve”, but as we explore further, it really isn’t that simple.

AMH stands for Anti-Mullerian Hormone. This hormone is produced by the granulosa cells, which are specific cells within a developing follicle.

Follicles take around 100 days to develop, and this must happen at a nice slow pace in order to reach ovulation. AMH is produced to prevent these delicate “pre-antral” follicles from being stimulated by Follicle Stimulating Hormone (FSH) too early. [Pre-antral means they they have left the “storage cupboard” but are now at the stage before they reach the final menstrual month where they will be competing for ovulation.]

The larger the follicles get, the more AMH they produce, until they are ready to be stimulated by FSH within the menstrual month.

Therefore, AMH levels can be used as an indicator of the number of antral or developing follicles you might have. However, this is not as simple as it sounds. It is not an indicator of dormant eggs you still have in “storage” i.e. total ovarian reserve.

In theory, if your AMH is low, this could mean that you don’t have many antral follicles coming up along the “production line”, and thus not producing as much AMH, but those that you do have could be a good size and of good quality. In contrast, you might have lots of antral follicles but not of a good size and not developing particularly well, and thus not producing much AMH.

So really, AMH is not a good indicator for determining your complete ovarian reserve. What it is useful for is for IVF clinics to gauge an idea of how many follicles they might be able to work with during an IVF cycle. But without considering other factors, a fully rounded picture cannot be seen.

Other factors to consider

Age is the main factor when looking at fertility. There will be a slow and natural decrease in AMH as we get older.

If you are a younger woman with low AMH for your age group, there are other factors to consider including vitamin and mineral deficiencies, blood flow to the pelvis, inflammation and autoimmune responses, contraceptive drugs, smoking/vaping, sleep quality, stress, infections. All of these factors can have a significant impact on the ovarian environment, and with improvements in place, AMH can rise.

My advice would be not to get fixated on AMH levels, and certainly do not look at them in isolation. Take a good look at both your own and your partner’s overall health and lifestyle, get support from an holistic practitioner. Take time to make improvements to your diet and lifestyle (remember the 100 days) to do everything in your power to improve that internal environment within which eggs are recruited and developed, within which sperm are created, and the uterine terrain in which they come together to create new life.

Other useful information

Listen to this episode of Hannah Pearn’s podcast, talking about Low AMH and what it really means for your fertility

This is a great E-book if you want to know the answers to all the burning questions you have about low AMH: https://www.explaininginfertility.com/courses/LowAMH-ebook

This was a large study which measured AMH levels in a group of 1015 women who had no known fertility issues and who all had a proven level of fertility (conceived a child within 12 months of trying and carried to full term). Almost without exception, this presented those with low AMH were more likely to conceive. Thus, this research shows that it is possible to be naturally fertile with low AMH. https://pubmed.ncbi.nlm.nih.gov/24716733/